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产品目录

PARK2/Parkin/PRKN抗体图片
产品货号:
Z22960
中文名称:
PARK2/Parkin/PRKN抗体
英文名称:
Anti-PARK2/Parkin/PRKN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PARK2/Parkin/PRKN Antibody
指标别名AR JP;LPRS2;PARK2;PARK2/Parkin;Parkin;Parkinson disease protein 2;PDJ;PRKN
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC,ICC
基因名称PRKN
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Parkin recombinant protein (Position:I23-K416).Human Parkin shares 82% and 84% amino acid (aa) sequence identity with mouse and rat Parkin,respectively.
实际分子量66KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Parkin is a RING domain-containing E3 ubiquitin ligase involved in proteasome-dependent degradation of proteins.It is mapped to 6q26.This gene is important for mitochondrial quality control by lysosome-dependent degradation of damaged mitochondria through autophagy,or mitophagy.Parkin is expressed in neuronal processes and cell bodies of neurons,but not glial cells,in the midbrain,basal ganglia,cerebral cortex,and cerebellum.Parkin assimilated with actin filaments,suggesting that it is a cytoskeletal-associated protein.Parkin is identified as a transcriptional repressor of p53 independent of its ubiquitin ligase function.It also has been found that parkin was associated physically with mitochondrial DNA (mtDNA) in proliferating as well as in differentiated SH-SY5Y neuroblastoma cells.
Uniprot IDO60260
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称parkin RBR E3 ubiquitin protein ligase
蛋白名全称E3 ubiquitin-protein ligase parkin
推荐稀释比
Western blot(WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
Immunocytochemistry 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:PARK2/Parkin/PRKN抗体PARK2抗体Parkin抗体PRKN多抗Anti-PARK2/Parkin/PRKN Antibody
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